API cost decision in 10 seconds

NewMistral Medium 3.5 vs Claude Opus 4.5

Pick Mistral Medium 3.5 when budget and context both matter.

Page updated:  Data confirmed:  Prices normalized to USD per 1M tokens Sample workload: 1M input + 500K output

Budget verdict

Pick Mistral Medium 3.5 when budget and context both matter.

On the standard 1M input plus 500K output workload, Mistral Medium 3.5 is estimated at $5.25 vs $17.5 for Claude Opus 4.5, saving $12.25 (70% lower).

Cost-first pickMistral Medium 3.5
Context-first pickMistral Medium 3.5
Sample savings$12.2570%
10x traffic gap$122.5

Mistral Medium 3.5 is cheaper on the standard workload and also has the larger context window. At 10x that traffic, the same price gap is about $122.5. Use the calculator below to replace the sample workload with your own token volume.

Cost sensitivity

Workload Sensitivity

Same prices, different token mixes.

Mistral Medium 3.5 stays cheaper across input-heavy, balanced, and output-heavy sample workloads.

Workload shapeToken mixBetter pickMistral Medium 3.5Claude Opus 4.5
Input-heavy / RAG5M input + 500K outputMistral Medium 3.5$11.25$37.5
Balanced workload1M input + 1M outputMistral Medium 3.5$9$30
Output-heavy chatbot1M input + 5M outputMistral Medium 3.5$39$130
Cheaper input Mistral Medium 3.5 $1.5 vs $5 / 1M

Mistral Medium 3.5 is $3.5 cheaper per 1M input tokens (70% lower; 3.33x difference).

Cheaper output Mistral Medium 3.5 $7.5 vs $25 / 1M

Mistral Medium 3.5 is $17.5 cheaper per 1M output tokens (70% lower; 3.33x difference).

Larger context Mistral Medium 3.5 262.14K vs 200K

Mistral Medium 3.5 has 62.14K more context (1.31x larger).

Sample workload Mistral Medium 3.5 $5.25 vs $17.5

Mistral Medium 3.5 is $12.25 cheaper on the standard workload (70% lower).

Estimate your workload cost

Your Workload Cost

Prices are normalized to USD per 1M tokens.
Mistral Medium 3.5 Calculating… Estimated API cost
Claude Opus 4.5 Calculating… Estimated API cost
Cheaper for this workload Calculating… Difference: calculating…

This estimate uses normalized public API pricing per 1M tokens. It is a planning aid, not a billing quote. Verify provider pricing, limits, and terms before production use.

Quick Decision

Verdict

Mistral Medium 3.5 has the lower input price; Mistral Medium 3.5 has the lower output price; Mistral Medium 3.5 offers the larger context window. For the 1M input plus 500K output sample, Mistral Medium 3.5 is cheaper for the standard workload.

For a 1M input token plus 500K output token workload, the estimated API cost is $5.25 for Mistral Medium 3.5 and $17.5 for Claude Opus 4.5.

Best Fit

Choose Mistral Medium 3.5 when you care most about lower input-token price, lower output-token price, and larger context window.

Choose Claude Opus 4.5 when its provider, model quality, latency, or availability is more important than the numeric price/context winner.

Decision Notes
  • On the standard 1M input plus 500K output workload, Mistral Medium 3.5 is estimated at $5.25 vs $17.5 for Claude Opus 4.5, saving $12.25 (70% lower).
  • Mistral Medium 3.5 is $12.25 cheaper on the standard workload (70% lower).
  • Mistral Medium 3.5 is $3.5 cheaper per 1M input tokens (70% lower; 3.33x difference).
  • Mistral Medium 3.5 is $17.5 cheaper per 1M output tokens (70% lower; 3.33x difference).
  • Mistral Medium 3.5 has 62.14K more context (1.31x larger).
Head-to-Head Specs
FeatureNewMistral Medium 3.5
(Mistral)
Claude Opus 4.5
(Anthropic)
Input Price
prompt tokens per 1M
$1.5$5
Completion Price
per 1M tokens
$7.5$25
Sample Workload Cost
1M input + 500K output
$5.25$17.5
Context Window262.14K200K
Release Date

Use-Case Decision Matrix

Use caseBetter pickWhy
Budget-constrained productionMistral Medium 3.5On the standard 1M input plus 500K output workload, Mistral Medium 3.5 is estimated at $5.25 vs $17.5 for Claude Opus 4.5, saving $12.25 (70% lower).
High-volume input processingMistral Medium 3.5Lower prompt-token price matters most when prompts, retrieved passages, or documents dominate the bill.
Long responses and chatbotsMistral Medium 3.5Lower output-token price matters most when assistants generate many completion tokens.
RAG or long-document workMistral Medium 3.5A larger context window leaves more room for retrieved passages, conversation history, or source files.

Related Alternatives

Same-provider lower-cost swaps
  • Mistral Nemo can replace Mistral Medium 3.5 when lower sample workload cost matters most: $0.04.
  • Mistral Small 3 can replace Mistral Medium 3.5 when lower sample workload cost matters most: $0.09.
  • Ministral 3 3B 2512 can replace Mistral Medium 3.5 when lower sample workload cost matters most: $0.15.
  • Mistral Small 3.2 24B can replace Mistral Medium 3.5 when lower sample workload cost matters most: $0.17.
Larger context near this budget
  • Llama 4 Scout offers 10M context with $0.23 sample workload cost.
  • Grok 4.20 Multi-Agent offers 2M context with $5 sample workload cost.
  • Grok 4.20 offers 2M context with $2.5 sample workload cost.
  • GPT-5.5 offers 1.05M context with $20 sample workload cost.

Cheaper alternatives

Review low-cost models sorted by a standard 1M input plus 500K output workload.

Open cheapest models

Larger context alternatives

Find models with larger context windows for RAG, long documents, and codebase review.

Open largest context models

Provider catalogs

Compare models within provider hubs before choosing a final API vendor.

Open provider hubs

Mistral catalog

Review all tracked Mistral models before deciding whether this matchup is the right shortlist.

Open Mistral models

Anthropic catalog

Check other Anthropic models with comparable pricing, context, or release timing.

Open Anthropic models
Mistral Medium 3.5

Mistral Medium 3.5 is a dense 128B instruction-following model from Mistral AI. It supports text and image inputs with text output, and is designed for agentic workflows, coding, and complex...

Claude Opus 4.5

Claude Opus 4.5 is Anthropic’s frontier reasoning model optimized for complex software engineering, agentic workflows, and long-horizon computer use. It offers strong multimodal capabilities, competitive performance across real-world coding and...